The Spanish for “hand,” mano, has a first cousin in the English manufacture.

Manufacture comes from the Latin manus (like in Spanish, also “hand”) and the Latin factura (which is from facere — “to do”, and almost identically in Spanish, with an f‑to‑h conversion, hacer).

Thus, “manufacturing” is literally, “making by hand” — the work of an artisan!

Also from the Latin for “hand”, and thus still cousins with the Spanish mano is manual as well: manual labor is also work done with your hands – literally.